Cargando…

A PHF8 Homolog in C. elegans Promotes DNA Repair via Homologous Recombination

PHF8 is a JmjC domain-containing histone demethylase, defects in which are associated with X-linked mental retardation. In this study, we examined the roles of two PHF8 homologs, JMJD-1.1 and JMJD-1.2, in the model organism C. elegans in response to DNA damage. A deletion mutation in either of the g...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Changrim, Hong, Seokbong, Lee, Min Hye, Koo, Hyeon-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390335/
https://www.ncbi.nlm.nih.gov/pubmed/25853498
http://dx.doi.org/10.1371/journal.pone.0123865