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Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms

Epidemiological studies suggest a relationship between blood lipids and immune-mediated diseases, but the nature of these associations is not well understood. We used genome-wide association studies (GWAS) to investigate shared single nucleotide polymorphisms (SNPs) between blood lipids and immune-m...

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Detalles Bibliográficos
Autores principales: Andreassen, Ole A., Desikan, Rahul S., Wang, Yunpeng, Thompson, Wesley K., Schork, Andrew J., Zuber, Verena, Doncheva, Nadezhda T., Ellinghaus, Eva, Albrecht, Mario, Mattingsdal, Morten, Franke, Andre, Lie, Benedicte A., Mills, Ian, Aukrust, Pål, McEvoy, Linda K., Djurovic, Srdjan, Karlsen, Tom H., Dale, Anders M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390360/
https://www.ncbi.nlm.nih.gov/pubmed/25853426
http://dx.doi.org/10.1371/journal.pone.0123057