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Multi-generational Impact of Maternal Overnutrition/Obesity in the Sheep on the Neonatal Leptin Surge in Granddaughters

BACKGROUND/OBJECTIVES: We have reported that maternal overnutrition/obesity (OB) in sheep resulting from feeding 150% of National Research Council (NRC) requirements throughout gestation, leads to maternal hyperglycemia and hyperinsulinemia. Further, newborn lambs born to OB vs. control-fed (CON, 10...

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Detalles Bibliográficos
Autores principales: Shasa, Desiree R., Odhiambo, John F., Long, Nathan M., Tuersunjiang, Nuermaimaiti, Nathanielsz, Peter W., Ford, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390411/
https://www.ncbi.nlm.nih.gov/pubmed/25354845
http://dx.doi.org/10.1038/ijo.2014.190