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Prevention of oxaliplatin-induced peripheral neuropathy by a polyamine-reduced diet—NEUROXAPOL: protocol of a prospective, randomised, controlled, single-blind and monocentric trial

INTRODUCTION: Oxaliplatin remains the most widely used chemotherapeutic agent for treating advanced colorectal cancer but its efficacy is hampered by dose-limiting neurotoxicity manifested by a painful polyneuropathy. Oxaliplatin-induced peripheral neuropathy (OIPN) is characterised by acute and tra...

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Detalles Bibliográficos
Autores principales: Balayssac, David, Ferrier, Jérémy, Pereira, Bruno, Gillet, Brigitte, Pétorin, Caroline, Vein, Julie, Libert, Frédéric, Eschalier, Alain, Pezet, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390686/
https://www.ncbi.nlm.nih.gov/pubmed/25833669
http://dx.doi.org/10.1136/bmjopen-2014-007479