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Prevention of oxaliplatin-induced peripheral neuropathy by a polyamine-reduced diet—NEUROXAPOL: protocol of a prospective, randomised, controlled, single-blind and monocentric trial
INTRODUCTION: Oxaliplatin remains the most widely used chemotherapeutic agent for treating advanced colorectal cancer but its efficacy is hampered by dose-limiting neurotoxicity manifested by a painful polyneuropathy. Oxaliplatin-induced peripheral neuropathy (OIPN) is characterised by acute and tra...
Autores principales: | Balayssac, David, Ferrier, Jérémy, Pereira, Bruno, Gillet, Brigitte, Pétorin, Caroline, Vein, Julie, Libert, Frédéric, Eschalier, Alain, Pezet, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390686/ https://www.ncbi.nlm.nih.gov/pubmed/25833669 http://dx.doi.org/10.1136/bmjopen-2014-007479 |
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