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HFE gene mutation and oxidative damage biomarkers in patients with myelodysplastic syndromes and its relation to transfusional iron overload: an observational cross-sectional study

OBJECTIVE: A relation between transfusional IOL (iron overload), HFE status and oxidative damage was evaluated. DESIGN, SETTING AND PARTICIPANTS: An observational cross-sectional study involving 87 healthy individuals and 78 patients with myelodysplastic syndromes (MDS) with and without IOL, seen at...

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Detalles Bibliográficos
Autores principales: De Souza, Geane Felix, Ribeiro, Howard Lopes, De Sousa, Juliana Cordeiro, Heredia, Fabíola Fernandes, De Freitas, Rivelilson Mendes, Martins, Manoel Ricardo Alves, Gonçalves, Romélia Pinheiro, Pinheiro, Ronald Feitosa, Magalhães, Silvia Maria Meira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390728/
https://www.ncbi.nlm.nih.gov/pubmed/25841232
http://dx.doi.org/10.1136/bmjopen-2014-006048