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Characterization of Folding Cores in the Cyclophilin A-Cyclosporin A Complex

Determining the folding core of a protein yields information about its folding process and dynamics. The experimental procedures for identifying the amino acids that make up the folding core include hydrogen-deuterium exchange and Φ-value analysis and can be expensive and time consuming. Because of...

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Detalles Bibliográficos
Autores principales: Heal, Jack W., Wells, Stephen A., Blindauer, Claudia A., Freedman, Robert B., Römer, Rudolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390823/
https://www.ncbi.nlm.nih.gov/pubmed/25863065
http://dx.doi.org/10.1016/j.bpj.2015.02.017