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Characterization of Folding Cores in the Cyclophilin A-Cyclosporin A Complex
Determining the folding core of a protein yields information about its folding process and dynamics. The experimental procedures for identifying the amino acids that make up the folding core include hydrogen-deuterium exchange and Φ-value analysis and can be expensive and time consuming. Because of...
Autores principales: | Heal, Jack W., Wells, Stephen A., Blindauer, Claudia A., Freedman, Robert B., Römer, Rudolf A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390823/ https://www.ncbi.nlm.nih.gov/pubmed/25863065 http://dx.doi.org/10.1016/j.bpj.2015.02.017 |
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