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The Origin and Evolution of Ribonucleotide Reduction

Ribonucleotide reduction is the only pathway for de novo synthesis of deoxyribonucleotides in extant organisms. This chemically demanding reaction, which proceeds via a carbon-centered free radical, is catalyzed by ribonucleotide reductase (RNR). The mechanism has been deemed unlikely to be catalyze...

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Detalles Bibliográficos
Autores principales: Lundin, Daniel, Berggren, Gustav, Logan, Derek T., Sjöberg, Britt-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390871/
https://www.ncbi.nlm.nih.gov/pubmed/25734234
http://dx.doi.org/10.3390/life5010604