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Targeting cell cycle regulators in hematologic malignancies

Hematologic malignancies represent the fourth most frequently diagnosed cancer in economically developed countries. In hematologic malignancies normal hematopoiesis is interrupted by uncontrolled growth of a genetically altered stem or progenitor cell (HSPC) that maintains its ability of self-renewa...

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Detalles Bibliográficos
Autores principales: Aleem, Eiman, Arceci, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390903/
https://www.ncbi.nlm.nih.gov/pubmed/25914884
http://dx.doi.org/10.3389/fcell.2015.00016