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Chloroquine neither eliminates liver stage parasites nor delays their development in a murine Chemoprophylaxis Vaccination model

Chemoprophylaxis Vaccination (CVac) confers long lasting sterile protection against homologous parasite strains in humans, and involves inoculation of infectious sporozoites (SPZ) under drug cover. CVac using the drug chloroquine (CQ) induces pre-erythrocytic immunity in humans that includes antibod...

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Detalles Bibliográficos
Autores principales: Sahu, Tejram, Lambert, Lynn, Herrod, Jessica, Conteh, Solomon, Orr-Gonzalez, Sachy, Carter, Dariyen, Duffy, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391028/
https://www.ncbi.nlm.nih.gov/pubmed/25914686
http://dx.doi.org/10.3389/fmicb.2015.00283