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Chloroquine neither eliminates liver stage parasites nor delays their development in a murine Chemoprophylaxis Vaccination model
Chemoprophylaxis Vaccination (CVac) confers long lasting sterile protection against homologous parasite strains in humans, and involves inoculation of infectious sporozoites (SPZ) under drug cover. CVac using the drug chloroquine (CQ) induces pre-erythrocytic immunity in humans that includes antibod...
Autores principales: | Sahu, Tejram, Lambert, Lynn, Herrod, Jessica, Conteh, Solomon, Orr-Gonzalez, Sachy, Carter, Dariyen, Duffy, Patrick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391028/ https://www.ncbi.nlm.nih.gov/pubmed/25914686 http://dx.doi.org/10.3389/fmicb.2015.00283 |
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