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Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma

BACKGROUND: SIRT1 is a member of the mammalian sirtuin family with the ability to deacetylate histone and nonhistone proteins. The correlation between SIRT1 expression and tumor metastasis in several types of cancer has aroused widespread concern. This study investigated SIRT1 expression and its pro...

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Detalles Bibliográficos
Autores principales: Hao, Chong, Zhu, Peng-Xi, Yang, Xue, Han, Zhi-Peng, Jiang, Jing-Hua, Zong, Chen, Zhang, Xu-Guang, Liu, Wen-Ting, Zhao, Qiu-Dong, Fan, Ting-Ting, Zhang, Li, Wei, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391082/
https://www.ncbi.nlm.nih.gov/pubmed/25522783
http://dx.doi.org/10.1186/1471-2407-14-978