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Can the activation of plasminogen/plasmin system of the host by metabolic products of Dirofilaria immitis participate in heartworm disease endarteritis?

BACKGROUND: Proliferative endarteritis is one of the key pathological mechanisms of cardiopulmonary dirofilariosis, a cosmopolitan parasitosis caused by Dirofilaria immitis affecting dogs and cats around the world. It has been shown that the excretory/secretory antigens from D. immitis adult worms (...

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Detalles Bibliográficos
Autores principales: González-Miguel, Javier, Morchón, Rodrigo, Carretón, Elena, Montoya-Alonso, José Alberto, Simón, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391138/
https://www.ncbi.nlm.nih.gov/pubmed/25888952
http://dx.doi.org/10.1186/s13071-015-0799-0