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A multiplexed, targeted mass spectrometry assay of the S100 protein family uncovers the isoform-specific expression in thyroid tumours

BACKGROUND: Mounting evidence demonstrates a causal role for S100 proteins in tumourigenesis and several S100 isoforms have shown utility as biomarkers of several types of cancer. The S100 family is comprised of 21 small isoforms, many of them implicated in important cellular functions such as proli...

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Detalles Bibliográficos
Autores principales: Martínez-Aguilar, Juan, Clifton-Bligh, Roderick, Molloy, Mark P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391164/
https://www.ncbi.nlm.nih.gov/pubmed/25880590
http://dx.doi.org/10.1186/s12885-015-1217-x