Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques

Alzheimer's disease is a severe neurodegenerative disorder of the brain, pathologically characterized by extracellular beta-amyloid plaques, intraneuronal Tau inclusions, inflammation, reactive glial cells, vascular pathology and neuronal cell death. The degradation and clearance of beta-amyloi...

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Detalles Bibliográficos
Autor principal: Humpel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391240/
https://www.ncbi.nlm.nih.gov/pubmed/25914642
http://dx.doi.org/10.3389/fnagi.2015.00047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391240/
https://www.ncbi.nlm.nih.gov/pubmed/25914642
http://dx.doi.org/10.3389/fnagi.2015.00047

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