Reduction in focal ictal activity following transplantation of MGE interneurons requires expression of the GABA(A) receptor α4 subunit

Despite numerous advances, treatment-resistant seizures remain an important problem. Loss of neuronal inhibition is present in a variety of epilepsy models and is suggested as a mechanism for increased excitability, leading to the proposal that grafting inhibitory interneurons into seizure foci migh...

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Detalles Bibliográficos
Autores principales: Jaiswal, Manoj K., Keros, Sotirios, Zhao, Mingrui, Inan, Melis, Schwartz, Theodore H., Anderson, Stewart A., Homanics, Gregg E., Goldstein, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391265/
https://www.ncbi.nlm.nih.gov/pubmed/25914623
http://dx.doi.org/10.3389/fncel.2015.00127

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