Lgr5+ Cells Regenerate Hair Cells via Proliferation and Direct Transdifferentiation in Damaged Neonatal Mouse Utricle

Recruitment of endogenous progenitors is critical during tissue repair. The inner ear utricle requires mechanosensory hair cells (HCs) to detect linear acceleration. After damage, non-mammalian utricles regenerate HCs via both proliferation and direct transdifferentiation. In adult mammals, limited...

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Detalles Bibliográficos
Autores principales: Wang, Tian, Chai, Renjie, Kim, Grace S., Pham, Nicole, Jansson, Lina, Nguyen, Duc-Huy, Kuo, Bryan, May, Lindsey, Zuo, Jian, Cunningham, Lisa L., Cheng, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391285/
https://www.ncbi.nlm.nih.gov/pubmed/25849379
http://dx.doi.org/10.1038/ncomms7613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391285/
https://www.ncbi.nlm.nih.gov/pubmed/25849379
http://dx.doi.org/10.1038/ncomms7613

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