The anti-tumor efficacy of 2-deoxyglucose and D-allose are enhanced with p38 inhibition in pancreatic and ovarian cell lines

PURPOSE: The anti-tumor activity of glucose analogs 2-deoxy-glucose (2-DG) and D-allose was investigated alone or in combination with p38 mitogen-activated protein kinase (MAPK) inhibitor SB202190 or platinum analogs as a strategy to pharmacologically target glycolytic tumor phenotypes. METHODS: Hyp...

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Detalles Bibliográficos
Autores principales: Malm, Scott W, Hanke, Neale T, Gill, Alexander, Carbajal, Liliana, Baker, Amanda F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391305/
https://www.ncbi.nlm.nih.gov/pubmed/25888489
http://dx.doi.org/10.1186/s13046-015-0147-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391305/
https://www.ncbi.nlm.nih.gov/pubmed/25888489
http://dx.doi.org/10.1186/s13046-015-0147-4

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