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Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia

BACKGROUND: Evidence from cachectic cancer patients and animal models of cancer cachexia supports the involvement of Forkhead box O (FoxO) transcription factors in driving cancer-induced skeletal muscle wasting. However, the genome-wide gene networks and associated biological processes regulated by...

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Detalles Bibliográficos
Autores principales: Judge, Sarah M, Wu, Chia-Ling, Beharry, Adam W, Roberts, Brandon M, Ferreira, Leonardo F, Kandarian, Susan C, Judge, Andrew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391468/
https://www.ncbi.nlm.nih.gov/pubmed/25539728
http://dx.doi.org/10.1186/1471-2407-14-997