Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma

The alteration of the epidermal growth factor receptor (EGFR)-driven signaling network is a characteristic feature of glioblastomas (GBM), and its inhibition represents a treatment strategy. However, EGFR-targeted interventions have been largely ineffective. Complex perturbations in this system are...

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Detalles Bibliográficos
Autores principales: Azuaje, Francisco, Tiemann, Katja, Niclou, Simone P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391485/
https://www.ncbi.nlm.nih.gov/pubmed/25885672
http://dx.doi.org/10.1186/s12964-015-0098-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391485/
https://www.ncbi.nlm.nih.gov/pubmed/25885672
http://dx.doi.org/10.1186/s12964-015-0098-6

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