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Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma
The alteration of the epidermal growth factor receptor (EGFR)-driven signaling network is a characteristic feature of glioblastomas (GBM), and its inhibition represents a treatment strategy. However, EGFR-targeted interventions have been largely ineffective. Complex perturbations in this system are...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391485/ https://www.ncbi.nlm.nih.gov/pubmed/25885672 http://dx.doi.org/10.1186/s12964-015-0098-6 |