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2.8 Å resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy

Recent developments in detector hardware and image-processing software have revolutionized single particle cryo-electron microscopy (cryoEM) and led to a wave of near-atomic resolution (typically ∼3.3 Å) reconstructions. Reaching resolutions higher than 3 Å is a prerequisite for structure-based drug...

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Detalles Bibliográficos
Autores principales: Campbell, Melody G, Veesler, David, Cheng, Anchi, Potter, Clinton S, Carragher, Bridget
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391500/
https://www.ncbi.nlm.nih.gov/pubmed/25760083
http://dx.doi.org/10.7554/eLife.06380