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Generating Customized Transgene Landing Sites and Multi-Transgene Arrays in Drosophila Using phiC31 Integrase

Transgenesis in numerous eukaryotes has been facilitated by the use of site-specific integrases to stably insert transgenes at predefined genomic positions (landing sites). However, the utility of integrase-mediated transgenesis in any system is constrained by the limited number and variable express...

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Detalles Bibliográficos
Autores principales: Knapp, Jon-Michael, Chung, Phuong, Simpson, Julie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391550/
https://www.ncbi.nlm.nih.gov/pubmed/25680812
http://dx.doi.org/10.1534/genetics.114.173187