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An Estimate of the Average Number of Recessive Lethal Mutations Carried by Humans
The effects of inbreeding on human health depend critically on the number and severity of recessive, deleterious mutations carried by individuals. In humans, existing estimates of these quantities are based on comparisons between consanguineous and nonconsanguineous couples, an approach that confoun...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391560/ https://www.ncbi.nlm.nih.gov/pubmed/25697177 http://dx.doi.org/10.1534/genetics.114.173351 |