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Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury

BACKGROUND: Neuregulin-1 (NRG-1) has been shown to act as a neuroprotectant in animal models of nerve agent intoxication and other acute brain injuries. We recently demonstrated that NRG-1 blocked delayed neuronal death in rats intoxicated with the organophosphate (OP) neurotoxin diisopropylfluropho...

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Detalles Bibliográficos
Autores principales: Li, Yonggang, Lein, Pamela J, Ford, Gregory D, Liu, Cuimei, Stovall, Kyndra C, White, Todd E, Bruun, Donald A, Tewolde, Teclemichael, Gates, Alicia S, Distel, Timothy J, Surles-Zeigler, Monique C, Ford, Byron D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391606/
https://www.ncbi.nlm.nih.gov/pubmed/25880399
http://dx.doi.org/10.1186/s12974-015-0283-y