Application of Long-Acting VLHL PAI-1 during Sutureless Partial Nephrectomy in Mice Reduces Bleeding

PAI-1 prevents lysis of blood clot by inhibiting the urokinase and tPA induced conversion of plasminogen to plasmin. VLHL PAI-1 protein mutant was created to extend half-life over 700 hours. The objective of this paper was to test VLHL PAI-1 effects on bleeding during partial nephrectomy in mice. Al...

Descripción completa

Detalles Bibliográficos
Autores principales: Shahrour, Khaled, Keck, Rick, Jankun, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391615/
https://www.ncbi.nlm.nih.gov/pubmed/25883959
http://dx.doi.org/10.1155/2015/392862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391615/
https://www.ncbi.nlm.nih.gov/pubmed/25883959
http://dx.doi.org/10.1155/2015/392862

Ejemplares similares