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Evaluation of (¹¹¹)In-Labelled Exendin-4 Derivatives Containing Different Meprin β-Specific Cleavable Linkers

BACKGROUND: Cleavable linkers, which are specifically cleaved by defined conditions or enzymes, are powerful tools that can be used for various purposes. Amongst other things, they have been successfully used to deliver toxic payloads as prodrugs into target tissues. In this work novel linker sequen...

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Detalles Bibliográficos
Autores principales: Jodal, Andreas, Pape, Fabienne, Becker-Pauly, Christoph, Maas, Ole, Schibli, Roger, Béhé, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391719/
https://www.ncbi.nlm.nih.gov/pubmed/25855967
http://dx.doi.org/10.1371/journal.pone.0123443