On the interactions of leflunomide and teriflunomide within receptor cavity — NMR studies and energy calculations

Leflunomide is a disease-modifying antirheumatic drug with antiinflammatory and immunosuppressive activity used for the treatment of psoriatic and rheumatoid arthritis. It undergoes rapid metabolization to teriflunomide, a metabolite that is responsible for the biological activity of leflunomide. Co...

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Detalles Bibliográficos
Autores principales: Kujawski, Jacek, Bernard, Marek K., Jodłowska, Elżbieta, Czaja, Kornelia, Drabińska, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391734/
https://www.ncbi.nlm.nih.gov/pubmed/25851105
http://dx.doi.org/10.1007/s00894-015-2643-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391734/
https://www.ncbi.nlm.nih.gov/pubmed/25851105
http://dx.doi.org/10.1007/s00894-015-2643-z

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