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Contribution of Large Region Joint Associations to Complex Traits Genetics

A polygenic model of inheritance, whereby hundreds or thousands of weakly associated variants contribute to a trait’s heritability, has been proposed to underlie the genetic architecture of complex traits. However, relatively few genetic variants have been positively identified so far and they colle...

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Detalles Bibliográficos
Autores principales: Paré, Guillaume, Asma, Senay, Deng, Wei Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391841/
https://www.ncbi.nlm.nih.gov/pubmed/25856144
http://dx.doi.org/10.1371/journal.pgen.1005103