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Contribution of Large Region Joint Associations to Complex Traits Genetics
A polygenic model of inheritance, whereby hundreds or thousands of weakly associated variants contribute to a trait’s heritability, has been proposed to underlie the genetic architecture of complex traits. However, relatively few genetic variants have been positively identified so far and they colle...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391841/ https://www.ncbi.nlm.nih.gov/pubmed/25856144 http://dx.doi.org/10.1371/journal.pgen.1005103 |