Cargando…
Contribution of Large Region Joint Associations to Complex Traits Genetics
A polygenic model of inheritance, whereby hundreds or thousands of weakly associated variants contribute to a trait’s heritability, has been proposed to underlie the genetic architecture of complex traits. However, relatively few genetic variants have been positively identified so far and they colle...
Autores principales: | Paré, Guillaume, Asma, Senay, Deng, Wei Q. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391841/ https://www.ncbi.nlm.nih.gov/pubmed/25856144 http://dx.doi.org/10.1371/journal.pgen.1005103 |
Ejemplares similares
-
A method to estimate the contribution of regional genetic associations to complex traits from summary association statistics
por: Pare, Guillaume, et al.
Publicado: (2016) -
A machine-learning heuristic to improve gene score prediction of polygenic traits
por: Paré, Guillaume, et al.
Publicado: (2017) -
Author Correction: A machine-learning heuristic to improve gene score prediction of polygenic traits
por: Paré, Guillaume, et al.
Publicado: (2019) -
Calibrated rare variant genetic risk scores for complex disease prediction using large exome sequence repositories
por: Lali, Ricky, et al.
Publicado: (2021) -
Common variation contributes to the genetic architecture of social communication traits
por: St Pourcain, Beate, et al.
Publicado: (2013)