Age-Related Onset of Obesity Corresponds with Metabolic Dysregulation and Altered Microglia Morphology in Mice Deficient for Ifitm Proteins

The IfitmDel mouse lacks all five of the Ifitm genes via LoxP deletion. This animal breeds normally with no obvious defect in development. The IfitmDel animals exhibit a steady and significantly enhanced weight gain relative to wild-type controls beginning about three months of age and under normal...

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Detalles Bibliográficos
Autores principales: Wee, Yin Shen, Weis, Janis J., Gahring, Lorise C., Rogers, Scott W., Weis, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391874/
https://www.ncbi.nlm.nih.gov/pubmed/25856311
http://dx.doi.org/10.1371/journal.pone.0123218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391874/
https://www.ncbi.nlm.nih.gov/pubmed/25856311
http://dx.doi.org/10.1371/journal.pone.0123218

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