The EBNA3 Family of Epstein-Barr Virus Nuclear Proteins Associates with the USP46/USP12 Deubiquitination Complexes to Regulate Lymphoblastoid Cell Line Growth

The Epstein-Barr virus (EBV) nuclear proteins EBNA3A, EBNA3B, and EBNA3C interact with the cell DNA binding protein RBPJ and regulate cell and viral genes. Repression of the CDKN2A tumor suppressor gene products p16(INK4A) and p14(ARF) by EBNA3A and EBNA3C is critical for EBV mediated transformation...

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Detalles Bibliográficos
Autores principales: Ohashi, Makoto, Holthaus, Amy M., Calderwood, Michael A., Lai, Chiou-Yan, Krastins, Bryan, Sarracino, David, Johannsen, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391933/
https://www.ncbi.nlm.nih.gov/pubmed/25855980
http://dx.doi.org/10.1371/journal.ppat.1004822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391933/
https://www.ncbi.nlm.nih.gov/pubmed/25855980
http://dx.doi.org/10.1371/journal.ppat.1004822

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