Dexamethasone as Adjuvant to Bupivacaine Prolongs the Duration of Thermal Antinociception and Prevents Bupivacaine-Induced Rebound Hyperalgesia via Regional Mechanism in a Mouse Sciatic Nerve Block Model

BACKGROUND: Dexamethasone has been studied as an effective adjuvant to prolong the analgesia duration of local anesthetics in peripheral nerve block. However, the route of action for dexamethasone and its potential neurotoxicity are still unclear. METHODS: A mouse sciatic nerve block model was used....

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Detalles Bibliográficos
Autores principales: An, Ke, Elkassabany, Nabil M., Liu, Jiabin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391940/
https://www.ncbi.nlm.nih.gov/pubmed/25856078
http://dx.doi.org/10.1371/journal.pone.0123459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391940/
https://www.ncbi.nlm.nih.gov/pubmed/25856078
http://dx.doi.org/10.1371/journal.pone.0123459

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