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A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B and T cell malignancies
Growing evidence suggests that microRNAs facilitate the cross-talk between transcriptional modules and signal transduction pathways. MYC and NOTCH1 contribute to the pathogenesis of lymphoid malignancies. NOTCH induces MYC, connecting two signaling programs that enhance oncogenicity. Here we show th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391979/ https://www.ncbi.nlm.nih.gov/pubmed/25311243 http://dx.doi.org/10.1038/leu.2014.302 |