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IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects

IL-35 is a newly discovered inhibitory cytokine secreted by regulatory T cells (Tregs) and may have therapeutic potential in several inflammatory disorders. Acute graft-versus-host disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation and caused by donor T cel...

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Detalles Bibliográficos
Autores principales: Liu, Yuejun, Wu, Yan, Wang, Ying, Cai, Yifeng, Hu, Bo, Bao, Guangming, Fang, Hongying, Zhao, Lixiang, Ma, Shoubao, Cheng, Qiao, Song, Yuan, Liu, Yonghao, Zhu, Ziling, Chang, Huirong, Yu, Xiao, Sun, Aining, Zhang, Yi, Vignali, Dario A. A., Wu, Depei, Liu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391991/
https://www.ncbi.nlm.nih.gov/pubmed/25363669
http://dx.doi.org/10.1038/leu.2014.310