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Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice

AIMS/HYPOTHESIS: The receptor for AGEs (RAGE) is linked to proinflammatory pathology in a range of tissues. The objective of this study was to assess the potential modulatory role of RAGE in diabetic retinopathy. METHODS: Diabetes was induced in wild-type (WT) and Rage (−/−) mice (also known as Ager...

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Detalles Bibliográficos
Autores principales: McVicar, Carmel M., Ward, Micheal, Colhoun, Liza M., Guduric-Fuchs, Jasenka, Bierhaus, Angelika, Fleming, Thomas, Schlotterer, Andreas, Kolibabka, Matthias, Hammes, Hans-Peter, Chen, Mei, Stitt, Alan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392170/
https://www.ncbi.nlm.nih.gov/pubmed/25687235
http://dx.doi.org/10.1007/s00125-015-3523-x