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Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways
OBJECTIVES: Intestinal epithelial cells (IEC) express toll-like receptors (TLR) that facilitate microbial recognition. Stimulation of TLR ligands induces a transient increase in epithelial cell shedding, a mechanism that serves the antibacterial and antiviral host defence of the epithelium and promo...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392221/ https://www.ncbi.nlm.nih.gov/pubmed/25379949 http://dx.doi.org/10.1136/gutjnl-2014-307226 |