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Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways

OBJECTIVES: Intestinal epithelial cells (IEC) express toll-like receptors (TLR) that facilitate microbial recognition. Stimulation of TLR ligands induces a transient increase in epithelial cell shedding, a mechanism that serves the antibacterial and antiviral host defence of the epithelium and promo...

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Detalles Bibliográficos
Autores principales:	Günther, Claudia, Buchen, Barbara, He, Gui-Wei, Hornef, Mathias, Torow, Natalia, Neumann, Helmut, Wittkopf, Nadine, Martini, Eva, Basic, Marijana, Bleich, André, Watson, Alastair J M, Neurath, Markus F, Becker, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2015
Materias:	Small Bowel
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392221/ https://www.ncbi.nlm.nih.gov/pubmed/25379949 http://dx.doi.org/10.1136/gutjnl-2014-307226

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