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Discovering Che-1/AATF: a new attractive target for cancer therapy

The transcriptional cofactor Che-1/AATF is currently emerging as an important component of the DNA damage response (DDR) machinery, the complex signaling network that maintains genome integrity and prevents tumorigenesis. Moreover this protein is involved in a wide range of cellular pathways, regula...

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Detalles Bibliográficos
Autores principales: Iezzi, Simona, Fanciulli, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392318/
https://www.ncbi.nlm.nih.gov/pubmed/25914721
http://dx.doi.org/10.3389/fgene.2015.00141