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An antioxidant response is involved in resistance of Giardia duodenalis to albendazole

Albendazole (ABZ) is a therapeutic benzimidazole used to treat giardiasis that targets β-tubulin. However, the molecular bases of ABZ resistance in Giardia duodenalis are not understood because β-tubulin in ABZ-resistant clones lacks mutations explaining drug resistance. In previous work we compared...

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Detalles Bibliográficos
Autores principales: Argüello-García, Raúl, Cruz-Soto, Maricela, González-Trejo, Rolando, Paz-Maldonado, Luz María T., Bazán-Tejeda, M. Luisa, Mendoza-Hernández, Guillermo, Ortega-Pierres, Guadalupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392323/
https://www.ncbi.nlm.nih.gov/pubmed/25914688
http://dx.doi.org/10.3389/fmicb.2015.00286