Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores

The Chromosomal Passenger Complex (CPC) localizes to centromeres where it activates the mitotic checkpoint in response to inappropriate inter-kinetochore tension. This error correction function is essential for proper chromosome segregation. Here we define several critical features of CPC localizati...

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Detalles Bibliográficos
Autores principales: Bekier, Michael E., Mazur, Travis, Rashid, Maisha S., Taylor, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392389/
https://www.ncbi.nlm.nih.gov/pubmed/25854549
http://dx.doi.org/10.1038/ncomms7775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392389/
https://www.ncbi.nlm.nih.gov/pubmed/25854549
http://dx.doi.org/10.1038/ncomms7775

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