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Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores
The Chromosomal Passenger Complex (CPC) localizes to centromeres where it activates the mitotic checkpoint in response to inappropriate inter-kinetochore tension. This error correction function is essential for proper chromosome segregation. Here we define several critical features of CPC localizati...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392389/ https://www.ncbi.nlm.nih.gov/pubmed/25854549 http://dx.doi.org/10.1038/ncomms7775 |