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Structure of a 13-fold superhelix (almost) determined from first principles

Nuclear hormone receptors are cytoplasm-based transcription factors that bind a ligand, translate to the nucleus and initiate gene transcription in complex with a co-activator such as TIF2 (transcriptional intermediary factor 2). For structural studies the co-activator is usually mimicked by a pepti...

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Detalles Bibliográficos
Autores principales: Schoch, Guillaume A., Sammito, Massimo, Millán, Claudia, Usón, Isabel, Rudolph, Markus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392412/
https://www.ncbi.nlm.nih.gov/pubmed/25866655
http://dx.doi.org/10.1107/S2052252515000238