LKB1 Knockout Mouse Develops Spontaneous Atrial Fibrillation and Provides Mechanistic Insights Into Human Disease Process

BACKGROUND: Atrial fibrillation (AF) is a complex disease process, and the molecular mechanisms underlying initiation and progression of the disease are unclear. Consequently, AF has been difficult to model. In this study, we have presented a novel transgenic mouse model of AF that mimics human dise...

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Detalles Bibliográficos
Autores principales: Ozcan, Cevher, Battaglia, Emily, Young, Rebeccah, Suzuki, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392447/
https://www.ncbi.nlm.nih.gov/pubmed/25773299
http://dx.doi.org/10.1161/JAHA.114.001733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392447/
https://www.ncbi.nlm.nih.gov/pubmed/25773299
http://dx.doi.org/10.1161/JAHA.114.001733

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