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Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines

BACKGROUND: The ability to undertake controlled human malaria infection (CHMI) studies for preliminary evaluation of malaria vaccine candidates and anti-malaria drug efficacy has been limited by the need for access to sporozoite infected mosquitoes, aseptic, purified, cryopreserved sporozoites or bl...

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Detalles Bibliográficos
Autores principales: Stanisic, Danielle I, Liu, Xue Q, De, Sai Lata, Batzloff, Michael R, Forbes, Tanya, Davis, Christopher B, Sekuloski, Silvana, Chavchich, Marina, Chung, Wendy, Trenholme, Katharine, McCarthy, James S, Li, Tao, Sim, B Kim Lee, Hoffman, Stephen L, Good, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392471/
https://www.ncbi.nlm.nih.gov/pubmed/25890156
http://dx.doi.org/10.1186/s12936-015-0663-x