Cargando…

Increased H(+) efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression

Intracellular pH (pHi) dynamics is increasingly recognized as an important regulator of a range of normal and pathological cell behaviors. Notably, increased pHi is now acknowledged as a conserved characteristic of cancers and in cell models is confirmed to increase proliferation and migration as we...

Descripción completa

Detalles Bibliográficos
Autores principales: Grillo-Hill, Bree K, Choi, Changhoon, Jimenez-Vidal, Maite, Barber, Diane L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392478/
https://www.ncbi.nlm.nih.gov/pubmed/25793441
http://dx.doi.org/10.7554/eLife.03270