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Increased H(+) efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression
Intracellular pH (pHi) dynamics is increasingly recognized as an important regulator of a range of normal and pathological cell behaviors. Notably, increased pHi is now acknowledged as a conserved characteristic of cancers and in cell models is confirmed to increase proliferation and migration as we...
Autores principales: | Grillo-Hill, Bree K, Choi, Changhoon, Jimenez-Vidal, Maite, Barber, Diane L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392478/ https://www.ncbi.nlm.nih.gov/pubmed/25793441 http://dx.doi.org/10.7554/eLife.03270 |
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