Sirt7 promotes gastric cancer growth and inhibits apoptosis by epigenetically inhibiting miR-34a

Gastric cancer is the fourth most common cancer worldwide, with a low 5-year survival rate. Epigenetic modification plays pivotal roles in gastric cancer development. However, the role of histone-modifying enzymes in gastric cancer remains largely unknown. Here we report that Sirt7, a NAD(+)-depende...

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Detalles Bibliográficos
Autores principales: Zhang, Shun, Chen, Ping, Huang, Zuoan, Hu, Xiaorong, Chen, Mengting, Hu, Shanshan, Hu, Yixin, Cai, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392652/
https://www.ncbi.nlm.nih.gov/pubmed/25860861
http://dx.doi.org/10.1038/srep09787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392652/
https://www.ncbi.nlm.nih.gov/pubmed/25860861
http://dx.doi.org/10.1038/srep09787

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